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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VGF
Full Name:
Neurosecretory protein VGF
Alias:
Neuro-endocrine specific protein VGF; Neuro-endocrine specific VGF; Neurosecretory protein VGF; VGF nerve growth factor inducible
Type:
Secreted protein
Mass (Da):
67239
Number AA:
615
UniProt ID:
O15240
International Prot ID:
IPI00289501
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0008083
PhosphoSite+
KinaseNET
Biological Process:
GO:0051591
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
E
A
Q
P
P
P
L
S
S
E
H
K
E
P
V
Site 2
S37
A
Q
P
P
P
L
S
S
E
H
K
E
P
V
A
Site 3
S55
V
P
G
P
K
D
G
S
A
P
E
V
R
G
A
Site 4
S65
E
V
R
G
A
R
N
S
E
P
Q
D
E
G
E
Site 5
S95
Q
A
L
D
R
P
A
S
P
P
A
P
S
G
S
Site 6
S102
S
P
P
A
P
S
G
S
Q
Q
G
P
E
E
E
Site 7
T116
E
A
A
E
A
L
L
T
E
T
V
R
S
Q
T
Site 8
T118
A
E
A
L
L
T
E
T
V
R
S
Q
T
H
S
Site 9
S121
L
L
T
E
T
V
R
S
Q
T
H
S
L
P
A
Site 10
T123
T
E
T
V
R
S
Q
T
H
S
L
P
A
P
E
Site 11
S125
T
V
R
S
Q
T
H
S
L
P
A
P
E
S
P
Site 12
S131
H
S
L
P
A
P
E
S
P
E
P
A
A
P
P
Site 13
T142
A
A
P
P
R
P
Q
T
P
E
N
G
P
E
A
Site 14
S150
P
E
N
G
P
E
A
S
D
P
S
E
E
L
E
Site 15
S161
E
E
L
E
A
L
A
S
L
L
Q
E
L
R
D
Site 16
S170
L
Q
E
L
R
D
F
S
P
S
S
A
K
R
Q
Site 17
S172
E
L
R
D
F
S
P
S
S
A
K
R
Q
Q
E
Site 18
S173
L
R
D
F
S
P
S
S
A
K
R
Q
Q
E
T
Site 19
T191
E
T
E
T
R
T
H
T
L
T
R
V
N
L
E
Site 20
T193
E
T
R
T
H
T
L
T
R
V
N
L
E
S
P
Site 21
S199
L
T
R
V
N
L
E
S
P
G
P
E
R
V
W
Site 22
S209
P
E
R
V
W
R
A
S
W
G
E
F
Q
A
R
Site 23
S229
P
L
P
P
P
A
P
S
Q
F
Q
A
R
M
P
Site 24
S238
F
Q
A
R
M
P
D
S
G
P
L
P
E
T
H
Site 25
T244
D
S
G
P
L
P
E
T
H
K
F
G
E
G
V
Site 26
S253
K
F
G
E
G
V
S
S
P
K
T
H
L
G
E
Site 27
T256
E
G
V
S
S
P
K
T
H
L
G
E
A
L
A
Site 28
S284
P
K
A
R
R
P
E
S
A
L
L
G
G
S
E
Site 29
S360
E
A
A
E
E
R
E
S
A
R
E
E
E
E
A
Site 30
S420
A
G
A
E
D
K
R
S
Q
E
E
T
P
G
H
Site 31
T424
D
K
R
S
Q
E
E
T
P
G
H
R
R
K
E
Site 32
T435
R
R
K
E
A
E
G
T
E
E
G
G
E
E
E
Site 33
T451
D
E
E
M
D
P
Q
T
I
D
S
L
I
E
L
Site 34
S454
M
D
P
Q
T
I
D
S
L
I
E
L
S
T
K
Site 35
T460
D
S
L
I
E
L
S
T
K
L
H
L
P
A
D
Site 36
T501
P
R
A
A
P
A
P
T
H
V
R
S
P
Q
P
Site 37
S505
P
A
P
T
H
V
R
S
P
Q
P
P
P
P
A
Site 38
Y538
D
R
E
E
D
E
V
Y
P
P
G
P
Y
H
P
Site 39
Y549
P
Y
H
P
F
P
N
Y
I
R
P
R
T
L
Q
Site 40
T554
P
N
Y
I
R
P
R
T
L
Q
P
P
S
A
L
Site 41
S559
P
R
T
L
Q
P
P
S
A
L
R
R
R
H
Y
Site 42
Y566
S
A
L
R
R
R
H
Y
H
H
A
L
P
P
S
Site 43
S573
Y
H
H
A
L
P
P
S
R
H
Y
P
G
R
E
Site 44
Y576
A
L
P
P
S
R
H
Y
P
G
R
E
A
Q
A
Site 45
Y606
E
Q
E
E
L
E
N
Y
I
E
H
V
L
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation