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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD28
Full Name:
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
Alias:
Ankyrin repeat domain 28; Ankyrin repeat domain-containing protein 28; ANR28; KIAA0379; Phosphatase interactor targeting protein hnRNP K; PITK
Type:
Protein phosphatase, regulatory subunit
Mass (Da):
116543
Number AA:
1086
UniProt ID:
O15084
International Prot ID:
IPI00514769
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
L
E
E
V
E
D
E
S
P
A
F
I
S
K
L
Site 2
S21
D
E
S
P
A
F
I
S
K
L
P
Q
E
N
K
Site 3
S29
K
L
P
Q
E
N
K
S
L
H
S
P
P
S
G
Site 4
S32
Q
E
N
K
S
L
H
S
P
P
S
G
N
V
L
Site 5
S35
K
S
L
H
S
P
P
S
G
N
V
L
V
R
Y
Site 6
T76
F
Q
D
N
E
K
R
T
P
L
H
A
A
A
Y
Site 7
S105
A
R
V
N
A
K
D
S
K
W
L
T
P
L
H
Site 8
T109
A
K
D
S
K
W
L
T
P
L
H
R
A
V
A
Site 9
S117
P
L
H
R
A
V
A
S
C
S
E
E
A
V
Q
Site 10
T142
A
R
D
K
N
W
Q
T
P
L
H
I
A
A
A
Site 11
S239
V
T
C
K
D
K
K
S
Y
T
P
L
H
A
A
Site 12
T241
C
K
D
K
K
S
Y
T
P
L
H
A
A
A
S
Site 13
Y271
D
M
N
E
P
N
A
Y
G
N
T
P
L
H
V
Site 14
T274
E
P
N
A
Y
G
N
T
P
L
H
V
A
C
Y
Site 15
T307
Q
K
N
E
K
G
F
T
P
L
H
F
A
A
A
Site 16
S336
G
A
D
V
N
M
K
S
K
D
G
K
T
P
L
Site 17
T341
M
K
S
K
D
G
K
T
P
L
H
M
T
A
L
Site 18
S353
T
A
L
H
G
R
F
S
R
S
Q
T
I
I
Q
Site 19
S355
L
H
G
R
F
S
R
S
Q
T
I
I
Q
S
G
Site 20
T357
G
R
F
S
R
S
Q
T
I
I
Q
S
G
A
V
Site 21
T374
C
E
D
K
N
G
N
T
P
L
H
I
A
A
R
Site 22
T398
L
I
T
S
G
A
D
T
A
K
R
G
I
H
G
Site 23
S427
C
C
R
K
L
L
S
S
G
F
D
I
D
T
P
Site 24
T433
S
S
G
F
D
I
D
T
P
D
D
F
G
R
T
Site 25
S473
K
K
D
K
F
G
R
S
P
L
H
Y
A
A
A
Site 26
Y477
F
G
R
S
P
L
H
Y
A
A
A
N
C
N
Y
Site 27
T506
D
L
D
E
R
G
C
T
P
L
H
Y
A
A
T
Site 28
Y510
R
G
C
T
P
L
H
Y
A
A
T
S
D
T
D
Site 29
T516
H
Y
A
A
T
S
D
T
D
G
K
C
L
E
Y
Site 30
Y523
T
D
G
K
C
L
E
Y
L
L
R
N
D
A
N
Site 31
Y539
G
I
R
D
K
Q
G
Y
N
A
V
H
Y
S
A
Site 32
Y544
Q
G
Y
N
A
V
H
Y
S
A
A
Y
G
H
R
Site 33
S570
L
D
V
L
M
E
T
S
G
T
D
M
L
S
D
Site 34
T572
V
L
M
E
T
S
G
T
D
M
L
S
D
S
D
Site 35
S576
T
S
G
T
D
M
L
S
D
S
D
N
R
A
T
Site 36
S578
G
T
D
M
L
S
D
S
D
N
R
A
T
I
S
Site 37
T583
S
D
S
D
N
R
A
T
I
S
P
L
H
L
A
Site 38
S585
S
D
N
R
A
T
I
S
P
L
H
L
A
A
Y
Site 39
Y592
S
P
L
H
L
A
A
Y
H
G
H
H
Q
A
L
Site 40
S614
L
D
L
D
V
R
N
S
S
G
R
T
P
L
D
Site 41
S615
D
L
D
V
R
N
S
S
G
R
T
P
L
D
L
Site 42
T618
V
R
N
S
S
G
R
T
P
L
D
L
A
A
F
Site 43
T652
K
D
Y
I
L
K
R
T
P
I
H
A
A
A
T
Site 44
S693
G
Q
T
P
L
M
L
S
V
L
N
G
H
T
D
Site 45
Y703
N
G
H
T
D
C
V
Y
S
L
L
N
K
G
A
Site 46
S704
G
H
T
D
C
V
Y
S
L
L
N
K
G
A
N
Site 47
S750
A
K
C
L
L
R
D
S
R
G
R
T
P
I
H
Site 48
T754
L
R
D
S
R
G
R
T
P
I
H
L
S
A
A
Site 49
T784
S
M
D
A
N
P
A
T
A
D
N
H
G
Y
T
Site 50
S854
S
I
V
N
A
T
D
S
K
G
R
T
P
L
H
Site 51
T858
A
T
D
S
K
G
R
T
P
L
H
A
A
A
F
Site 52
S877
E
C
L
Q
L
L
L
S
H
N
A
Q
V
N
S
Site 53
S884
S
H
N
A
Q
V
N
S
V
D
S
T
G
K
T
Site 54
T888
Q
V
N
S
V
D
S
T
G
K
T
P
L
M
M
Site 55
T891
S
V
D
S
T
G
K
T
P
L
M
M
A
A
E
Site 56
T902
M
A
A
E
N
G
Q
T
N
T
V
E
M
L
V
Site 57
T904
A
E
N
G
Q
T
N
T
V
E
M
L
V
S
S
Site 58
T917
S
S
A
S
A
E
L
T
L
Q
D
N
S
K
N
Site 59
S922
E
L
T
L
Q
D
N
S
K
N
T
A
L
H
L
Site 60
S1022
T
M
M
P
V
S
S
S
S
P
L
S
S
L
T
Site 61
S1027
S
S
S
S
P
L
S
S
L
T
F
N
A
I
N
Site 62
T1029
S
S
P
L
S
S
L
T
F
N
A
I
N
R
Y
Site 63
T1037
F
N
A
I
N
R
Y
T
N
T
S
K
T
V
S
Site 64
S1040
I
N
R
Y
T
N
T
S
K
T
V
S
F
E
A
Site 65
T1042
R
Y
T
N
T
S
K
T
V
S
F
E
A
L
P
Site 66
S1044
T
N
T
S
K
T
V
S
F
E
A
L
P
I
M
Site 67
Y1058
M
R
N
E
P
S
S
Y
C
S
F
N
N
I
G
Site 68
S1060
N
E
P
S
S
Y
C
S
F
N
N
I
G
G
E
Site 69
Y1072
G
G
E
Q
E
Y
L
Y
T
D
V
D
E
L
N
Site 70
T1073
G
E
Q
E
Y
L
Y
T
D
V
D
E
L
N
D
Site 71
S1081
D
V
D
E
L
N
D
S
D
S
E
T
Y
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation