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Updated November 2019
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Protein Info
Short Name:
MAST4
Full Name:
Microtubule-associated serine/threonine-protein kinase 4
Alias:
EC 2.7.11.1; KIAA0303; Microtubule associated serine/threonine kinase family member 4
Type:
Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; AGC group; MAST family
Mass (Da):
284378
Number AA:
2626
UniProt ID:
O15021
International Prot ID:
IPI00307611
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
E
K
V
S
E
A
P
E
P
V
P
Site 2
S17
E
P
V
P
R
G
C
S
G
H
G
S
R
T
P
Site 3
S21
R
G
C
S
G
H
G
S
R
T
P
A
S
A
L
Site 4
T23
C
S
G
H
G
S
R
T
P
A
S
A
L
V
A
Site 5
S26
H
G
S
R
T
P
A
S
A
L
V
A
A
S
S
Site 6
S37
A
A
S
S
P
G
A
S
S
A
E
S
S
S
G
Site 7
S38
A
S
S
P
G
A
S
S
A
E
S
S
S
G
S
Site 8
S41
P
G
A
S
S
A
E
S
S
S
G
S
E
T
L
Site 9
S42
G
A
S
S
A
E
S
S
S
G
S
E
T
L
S
Site 10
S43
A
S
S
A
E
S
S
S
G
S
E
T
L
S
E
Site 11
S45
S
A
E
S
S
S
G
S
E
T
L
S
E
E
G
Site 12
T47
E
S
S
S
G
S
E
T
L
S
E
E
G
E
P
Site 13
S49
S
S
G
S
E
T
L
S
E
E
G
E
P
G
G
Site 14
S58
E
G
E
P
G
G
F
S
R
E
H
Q
P
P
P
Site 15
S111
V
P
P
A
P
R
G
S
S
A
S
Q
E
E
Q
Site 16
S112
P
P
A
P
R
G
S
S
A
S
Q
E
E
Q
D
Site 17
S114
A
P
R
G
S
S
A
S
Q
E
E
Q
D
E
E
Site 18
S127
E
E
L
D
H
I
L
S
P
P
P
M
P
F
R
Site 19
S137
P
M
P
F
R
K
C
S
N
P
D
V
A
S
G
Site 20
S143
C
S
N
P
D
V
A
S
G
P
G
K
S
L
K
Site 21
S148
V
A
S
G
P
G
K
S
L
K
Y
K
R
Q
L
Site 22
Y151
G
P
G
K
S
L
K
Y
K
R
Q
L
S
E
D
Site 23
S156
L
K
Y
K
R
Q
L
S
E
D
G
R
Q
L
R
Site 24
S166
G
R
Q
L
R
R
G
S
L
G
G
A
L
T
G
Site 25
S189
A
G
Q
A
W
P
A
S
A
E
T
S
N
L
V
Site 26
S193
W
P
A
S
A
E
T
S
N
L
V
R
M
R
S
Site 27
S200
S
N
L
V
R
M
R
S
Q
A
L
G
Q
S
A
Site 28
S206
R
S
Q
A
L
G
Q
S
A
P
S
L
T
A
S
Site 29
S209
A
L
G
Q
S
A
P
S
L
T
A
S
L
K
E
Site 30
S213
S
A
P
S
L
T
A
S
L
K
E
L
S
L
P
Site 31
S218
T
A
S
L
K
E
L
S
L
P
R
R
G
S
L
Site 32
S224
L
S
L
P
R
R
G
S
L
C
R
T
S
N
R
Site 33
T228
R
R
G
S
L
C
R
T
S
N
R
K
S
L
I
Site 34
S229
R
G
S
L
C
R
T
S
N
R
K
S
L
I
G
Site 35
S233
C
R
T
S
N
R
K
S
L
I
G
N
G
Q
S
Site 36
S240
S
L
I
G
N
G
Q
S
P
A
L
P
R
P
H
Site 37
S248
P
A
L
P
R
P
H
S
P
L
S
A
H
A
G
Site 38
S251
P
R
P
H
S
P
L
S
A
H
A
G
N
S
P
Site 39
S257
L
S
A
H
A
G
N
S
P
Q
D
S
P
R
N
Site 40
S261
A
G
N
S
P
Q
D
S
P
R
N
F
S
P
S
Site 41
S266
Q
D
S
P
R
N
F
S
P
S
A
S
A
H
F
Site 42
S268
S
P
R
N
F
S
P
S
A
S
A
H
F
S
F
Site 43
S270
R
N
F
S
P
S
A
S
A
H
F
S
F
A
R
Site 44
S274
P
S
A
S
A
H
F
S
F
A
R
S
L
N
R
Site 45
S278
A
H
F
S
F
A
R
S
L
N
R
T
D
G
R
Site 46
T282
F
A
R
S
L
N
R
T
D
G
R
R
W
S
L
Site 47
S288
R
T
D
G
R
R
W
S
L
A
S
L
P
S
S
Site 48
S291
G
R
R
W
S
L
A
S
L
P
S
S
G
Y
G
Site 49
S295
S
L
A
S
L
P
S
S
G
Y
G
T
N
T
P
Site 50
Y297
A
S
L
P
S
S
G
Y
G
T
N
T
P
S
S
Site 51
T299
L
P
S
S
G
Y
G
T
N
T
P
S
S
T
V
Site 52
T301
S
S
G
Y
G
T
N
T
P
S
S
T
V
S
S
Site 53
S303
G
Y
G
T
N
T
P
S
S
T
V
S
S
S
C
Site 54
S304
Y
G
T
N
T
P
S
S
T
V
S
S
S
C
S
Site 55
T305
G
T
N
T
P
S
S
T
V
S
S
S
C
S
S
Site 56
S307
N
T
P
S
S
T
V
S
S
S
C
S
S
Q
E
Site 57
S308
T
P
S
S
T
V
S
S
S
C
S
S
Q
E
K
Site 58
S309
P
S
S
T
V
S
S
S
C
S
S
Q
E
K
L
Site 59
S311
S
T
V
S
S
S
C
S
S
Q
E
K
L
H
Q
Site 60
S312
T
V
S
S
S
C
S
S
Q
E
K
L
H
Q
L
Site 61
Y321
E
K
L
H
Q
L
P
Y
Q
P
T
P
D
E
L
Site 62
T324
H
Q
L
P
Y
Q
P
T
P
D
E
L
H
F
L
Site 63
T337
F
L
S
K
H
F
C
T
T
E
S
I
A
T
E
Site 64
T338
L
S
K
H
F
C
T
T
E
S
I
A
T
E
N
Site 65
T343
C
T
T
E
S
I
A
T
E
N
R
C
R
N
T
Site 66
T350
T
E
N
R
C
R
N
T
P
M
R
P
R
S
R
Site 67
S356
N
T
P
M
R
P
R
S
R
S
L
S
P
G
R
Site 68
S358
P
M
R
P
R
S
R
S
L
S
P
G
R
S
P
Site 69
S360
R
P
R
S
R
S
L
S
P
G
R
S
P
A
C
Site 70
S364
R
S
L
S
P
G
R
S
P
A
C
C
D
H
E
Site 71
Y379
I
I
M
M
N
H
V
Y
K
E
R
F
P
K
A
Site 72
S400
R
L
K
E
I
I
T
S
Y
S
P
D
N
V
L
Site 73
S402
K
E
I
I
T
S
Y
S
P
D
N
V
L
P
L
Site 74
S432
A
R
D
C
L
D
K
S
H
Q
G
L
I
T
S
Site 75
T438
K
S
H
Q
G
L
I
T
S
R
Y
F
L
E
L
Site 76
S439
S
H
Q
G
L
I
T
S
R
Y
F
L
E
L
Q
Site 77
Y441
Q
G
L
I
T
S
R
Y
F
L
E
L
Q
H
K
Site 78
S460
L
Q
E
A
H
D
R
S
E
S
G
E
L
A
F
Site 79
S462
E
A
H
D
R
S
E
S
G
E
L
A
F
I
K
Site 80
Y498
F
D
P
E
E
F
Y
Y
L
L
E
A
A
E
G
Site 81
T515
K
E
G
Q
G
I
K
T
D
I
P
R
Y
I
I
Site 82
S523
D
I
P
R
Y
I
I
S
Q
L
G
L
N
K
D
Site 83
Y541
E
M
A
H
L
G
N
Y
D
S
G
T
A
E
T
Site 84
S543
A
H
L
G
N
Y
D
S
G
T
A
E
T
P
E
Site 85
T545
L
G
N
Y
D
S
G
T
A
E
T
P
E
T
D
Site 86
T548
Y
D
S
G
T
A
E
T
P
E
T
D
E
S
V
Site 87
T551
G
T
A
E
T
P
E
T
D
E
S
V
S
S
S
Site 88
S554
E
T
P
E
T
D
E
S
V
S
S
S
N
A
S
Site 89
S556
P
E
T
D
E
S
V
S
S
S
N
A
S
L
K
Site 90
S557
E
T
D
E
S
V
S
S
S
N
A
S
L
K
L
Site 91
S558
T
D
E
S
V
S
S
S
N
A
S
L
K
L
R
Site 92
S561
S
V
S
S
S
N
A
S
L
K
L
R
R
K
P
Site 93
S571
L
R
R
K
P
R
E
S
D
F
E
T
I
K
L
Site 94
T575
P
R
E
S
D
F
E
T
I
K
L
I
S
N
G
Site 95
Y588
N
G
A
Y
G
A
V
Y
F
V
R
H
K
E
S
Site 96
Y637
N
P
F
V
V
S
M
Y
C
S
F
E
T
R
R
Site 97
T660
V
E
G
G
D
C
A
T
L
M
K
N
M
G
P
Site 98
Y686
E
T
V
L
A
L
E
Y
L
H
N
Y
G
I
V
Site 99
Y690
A
L
E
Y
L
H
N
Y
G
I
V
H
R
D
L
Site 100
T726
K
V
G
L
M
S
M
T
T
N
L
Y
E
G
H
Site 101
T727
V
G
L
M
S
M
T
T
N
L
Y
E
G
H
I
Site 102
Y730
M
S
M
T
T
N
L
Y
E
G
H
I
E
K
D
Site 103
T749
L
D
K
Q
V
C
G
T
P
E
Y
I
A
P
E
Site 104
Y763
E
V
I
L
R
Q
G
Y
G
K
P
V
D
W
W
Site 105
T790
C
V
P
F
F
G
D
T
P
E
E
L
F
G
Q
Site 106
S800
E
L
F
G
Q
V
I
S
D
E
I
N
W
P
E
Site 107
T821
P
D
A
Q
D
L
I
T
L
L
L
R
Q
N
P
Site 108
T834
N
P
L
E
R
L
G
T
G
G
A
Y
E
V
K
Site 109
Y838
R
L
G
T
G
G
A
Y
E
V
K
Q
H
R
F
Site 110
S848
K
Q
H
R
F
F
R
S
L
D
W
N
S
L
L
Site 111
S853
F
R
S
L
D
W
N
S
L
L
R
Q
K
A
E
Site 112
S867
E
F
I
P
Q
L
E
S
E
D
D
T
S
Y
F
Site 113
T871
Q
L
E
S
E
D
D
T
S
Y
F
D
T
R
S
Site 114
S872
L
E
S
E
D
D
T
S
Y
F
D
T
R
S
E
Site 115
Y873
E
S
E
D
D
T
S
Y
F
D
T
R
S
E
K
Site 116
T876
D
D
T
S
Y
F
D
T
R
S
E
K
Y
H
H
Site 117
T892
E
T
E
E
E
D
D
T
N
D
E
D
F
N
V
Site 118
S905
N
V
E
I
R
Q
F
S
S
C
S
H
R
F
S
Site 119
S906
V
E
I
R
Q
F
S
S
C
S
H
R
F
S
K
Site 120
S908
I
R
Q
F
S
S
C
S
H
R
F
S
K
V
F
Site 121
S912
S
S
C
S
H
R
F
S
K
V
F
S
S
I
D
Site 122
S916
H
R
F
S
K
V
F
S
S
I
D
R
I
T
Q
Site 123
S917
R
F
S
K
V
F
S
S
I
D
R
I
T
Q
N
Site 124
T922
F
S
S
I
D
R
I
T
Q
N
S
A
E
E
K
Site 125
S925
I
D
R
I
T
Q
N
S
A
E
E
K
E
D
S
Site 126
S932
S
A
E
E
K
E
D
S
V
D
K
T
K
S
T
Site 127
T936
K
E
D
S
V
D
K
T
K
S
T
T
L
P
S
Site 128
S938
D
S
V
D
K
T
K
S
T
T
L
P
S
T
E
Site 129
T939
S
V
D
K
T
K
S
T
T
L
P
S
T
E
T
Site 130
S943
T
K
S
T
T
L
P
S
T
E
T
L
S
W
S
Site 131
T944
K
S
T
T
L
P
S
T
E
T
L
S
W
S
S
Site 132
T946
T
T
L
P
S
T
E
T
L
S
W
S
S
E
Y
Site 133
S948
L
P
S
T
E
T
L
S
W
S
S
E
Y
S
E
Site 134
S950
S
T
E
T
L
S
W
S
S
E
Y
S
E
M
Q
Site 135
S954
L
S
W
S
S
E
Y
S
E
M
Q
Q
L
S
T
Site 136
S960
Y
S
E
M
Q
Q
L
S
T
S
N
S
S
D
T
Site 137
T961
S
E
M
Q
Q
L
S
T
S
N
S
S
D
T
E
Site 138
S962
E
M
Q
Q
L
S
T
S
N
S
S
D
T
E
S
Site 139
S964
Q
Q
L
S
T
S
N
S
S
D
T
E
S
N
R
Site 140
S965
Q
L
S
T
S
N
S
S
D
T
E
S
N
R
H
Site 141
T967
S
T
S
N
S
S
D
T
E
S
N
R
H
K
L
Site 142
S969
S
N
S
S
D
T
E
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S
Site 294
T1857
S
G
K
K
N
D
T
T
S
A
R
E
L
S
P
Site 295
S1858
G
K
K
N
D
T
T
S
A
R
E
L
S
P
S
Site 296
S1863
T
T
S
A
R
E
L
S
P
S
S
L
K
M
N
Site 297
S1865
S
A
R
E
L
S
P
S
S
L
K
M
N
K
S
Site 298
S1866
A
R
E
L
S
P
S
S
L
K
M
N
K
S
Y
Site 299
S1872
S
S
L
K
M
N
K
S
Y
L
L
E
P
W
F
Site 300
S1883
E
P
W
F
L
P
P
S
R
G
L
Q
N
S
P
Site 301
S1889
P
S
R
G
L
Q
N
S
P
A
V
S
L
P
D
Site 302
S1893
L
Q
N
S
P
A
V
S
L
P
D
P
E
F
K
Site 303
T1909
D
R
K
G
P
H
P
T
A
R
S
P
G
T
V
Site 304
S1912
G
P
H
P
T
A
R
S
P
G
T
V
M
E
S
Site 305
T1915
P
T
A
R
S
P
G
T
V
M
E
S
N
P
Q
Site 306
S1919
S
P
G
T
V
M
E
S
N
P
Q
Q
R
E
G
Site 307
S1927
N
P
Q
Q
R
E
G
S
S
P
K
H
Q
D
H
Site 308
S1928
P
Q
Q
R
E
G
S
S
P
K
H
Q
D
H
T
Site 309
T1935
S
P
K
H
Q
D
H
T
T
D
P
K
L
L
T
Site 310
T1936
P
K
H
Q
D
H
T
T
D
P
K
L
L
T
C
Site 311
S1950
C
L
G
Q
N
L
H
S
P
D
L
A
R
P
R
Site 312
S1965
C
P
L
P
P
E
A
S
P
S
R
E
K
P
G
Site 313
S1967
L
P
P
E
A
S
P
S
R
E
K
P
G
L
R
Site 314
S1976
E
K
P
G
L
R
E
S
S
E
R
G
P
P
T
Site 315
S1977
K
P
G
L
R
E
S
S
E
R
G
P
P
T
A
Site 316
T1983
S
S
E
R
G
P
P
T
A
R
S
E
R
S
A
Site 317
S1986
R
G
P
P
T
A
R
S
E
R
S
A
A
R
A
Site 318
T1995
R
S
A
A
R
A
D
T
C
R
E
P
S
M
E
Site 319
S2000
A
D
T
C
R
E
P
S
M
E
L
C
F
P
E
Site 320
T2008
M
E
L
C
F
P
E
T
A
K
T
S
D
N
S
Site 321
T2011
C
F
P
E
T
A
K
T
S
D
N
S
K
N
L
Site 322
S2015
T
A
K
T
S
D
N
S
K
N
L
L
S
V
G
Site 323
S2020
D
N
S
K
N
L
L
S
V
G
R
T
H
P
D
Site 324
T2024
N
L
L
S
V
G
R
T
H
P
D
F
Y
T
Q
Site 325
Y2029
G
R
T
H
P
D
F
Y
T
Q
T
Q
A
M
E
Site 326
T2030
R
T
H
P
D
F
Y
T
Q
T
Q
A
M
E
K
Site 327
S2062
R
P
P
P
R
D
N
S
S
L
H
S
A
G
I
Site 328
S2063
P
P
P
R
D
N
S
S
L
H
S
A
G
I
P
Site 329
S2066
R
D
N
S
S
L
H
S
A
G
I
P
C
E
K
Site 330
S2094
E
A
L
L
A
R
R
S
L
Q
P
P
G
I
E
Site 331
S2102
L
Q
P
P
G
I
E
S
E
K
S
E
K
L
S
Site 332
S2105
P
G
I
E
S
E
K
S
E
K
L
S
S
F
P
Site 333
S2109
S
E
K
S
E
K
L
S
S
F
P
S
L
Q
K
Site 334
S2110
E
K
S
E
K
L
S
S
F
P
S
L
Q
K
D
Site 335
S2113
E
K
L
S
S
F
P
S
L
Q
K
D
G
A
K
Site 336
S2134
Q
P
L
Q
R
H
P
S
S
I
P
P
P
P
L
Site 337
S2135
P
L
Q
R
H
P
S
S
I
P
P
P
P
L
T
Site 338
T2142
S
I
P
P
P
P
L
T
A
K
D
L
S
S
P
Site 339
S2148
L
T
A
K
D
L
S
S
P
A
A
R
Q
H
C
Site 340
S2156
P
A
A
R
Q
H
C
S
S
P
S
H
A
S
G
Site 341
S2157
A
A
R
Q
H
C
S
S
P
S
H
A
S
G
R
Site 342
S2159
R
Q
H
C
S
S
P
S
H
A
S
G
R
E
P
Site 343
S2162
C
S
S
P
S
H
A
S
G
R
E
P
G
A
K
Site 344
S2171
R
E
P
G
A
K
P
S
T
A
E
P
S
S
S
Site 345
T2172
E
P
G
A
K
P
S
T
A
E
P
S
S
S
P
Site 346
S2176
K
P
S
T
A
E
P
S
S
S
P
Q
D
P
P
Site 347
S2177
P
S
T
A
E
P
S
S
S
P
Q
D
P
P
K
Site 348
S2178
S
T
A
E
P
S
S
S
P
Q
D
P
P
K
P
Site 349
S2190
P
K
P
V
A
A
H
S
E
S
S
S
H
K
P
Site 350
S2192
P
V
A
A
H
S
E
S
S
S
H
K
P
R
P
Site 351
S2194
A
A
H
S
E
S
S
S
H
K
P
R
P
G
P
Site 352
T2208
P
D
P
G
P
P
K
T
K
H
P
D
R
S
L
Site 353
S2214
K
T
K
H
P
D
R
S
L
S
S
Q
K
P
S
Site 354
S2216
K
H
P
D
R
S
L
S
S
Q
K
P
S
V
G
Site 355
S2217
H
P
D
R
S
L
S
S
Q
K
P
S
V
G
A
Site 356
S2221
S
L
S
S
Q
K
P
S
V
G
A
T
K
G
K
Site 357
T2225
Q
K
P
S
V
G
A
T
K
G
K
E
P
A
T
Site 358
T2232
T
K
G
K
E
P
A
T
Q
S
L
G
G
S
S
Site 359
S2234
G
K
E
P
A
T
Q
S
L
G
G
S
S
R
E
Site 360
S2238
A
T
Q
S
L
G
G
S
S
R
E
G
K
G
H
Site 361
S2246
S
R
E
G
K
G
H
S
K
S
G
P
D
V
F
Site 362
S2248
E
G
K
G
H
S
K
S
G
P
D
V
F
P
A
Site 363
T2256
G
P
D
V
F
P
A
T
P
G
S
Q
N
K
A
Site 364
S2259
V
F
P
A
T
P
G
S
Q
N
K
A
S
D
G
Site 365
S2264
P
G
S
Q
N
K
A
S
D
G
I
G
Q
G
E
Site 366
S2275
G
Q
G
E
G
G
P
S
V
P
L
H
T
D
R
Site 367
T2280
G
P
S
V
P
L
H
T
D
R
A
P
L
D
A
Site 368
S2293
D
A
K
P
Q
P
T
S
G
G
R
P
L
E
V
Site 369
S2316
R
P
G
H
P
G
P
S
E
P
A
D
Q
K
L
Site 370
T2331
S
A
V
G
E
K
Q
T
L
S
P
K
H
P
K
Site 371
S2333
V
G
E
K
Q
T
L
S
P
K
H
P
K
P
S
Site 372
S2340
S
P
K
H
P
K
P
S
T
V
K
D
C
P
T
Site 373
T2341
P
K
H
P
K
P
S
T
V
K
D
C
P
T
L
Site 374
T2347
S
T
V
K
D
C
P
T
L
C
K
Q
T
D
N
Site 375
T2357
K
Q
T
D
N
R
Q
T
D
K
S
P
S
Q
P
Site 376
S2360
D
N
R
Q
T
D
K
S
P
S
Q
P
A
A
N
Site 377
S2362
R
Q
T
D
K
S
P
S
Q
P
A
A
N
T
D
Site 378
T2368
P
S
Q
P
A
A
N
T
D
R
R
A
E
G
K
Site 379
Y2382
K
K
C
T
E
A
L
Y
A
P
A
E
G
D
K
Site 380
S2395
D
K
L
E
A
G
L
S
F
V
H
S
E
N
R
Site 381
S2399
A
G
L
S
F
V
H
S
E
N
R
L
K
G
A
Site 382
T2432
P
G
P
Q
K
P
P
T
E
A
D
K
P
N
G
Site 383
S2443
K
P
N
G
M
K
R
S
P
S
A
T
G
Q
S
Site 384
S2445
N
G
M
K
R
S
P
S
A
T
G
Q
S
S
F
Site 385
T2447
M
K
R
S
P
S
A
T
G
Q
S
S
F
R
S
Site 386
S2450
S
P
S
A
T
G
Q
S
S
F
R
S
T
A
L
Site 387
S2451
P
S
A
T
G
Q
S
S
F
R
S
T
A
L
P
Site 388
S2454
T
G
Q
S
S
F
R
S
T
A
L
P
E
K
S
Site 389
T2455
G
Q
S
S
F
R
S
T
A
L
P
E
K
S
L
Site 390
S2461
S
T
A
L
P
E
K
S
L
S
C
S
S
S
F
Site 391
S2463
A
L
P
E
K
S
L
S
C
S
S
S
F
P
E
Site 392
S2465
P
E
K
S
L
S
C
S
S
S
F
P
E
T
R
Site 393
S2466
E
K
S
L
S
C
S
S
S
F
P
E
T
R
A
Site 394
S2467
K
S
L
S
C
S
S
S
F
P
E
T
R
A
G
Site 395
T2471
C
S
S
S
F
P
E
T
R
A
G
V
R
E
A
Site 396
S2479
R
A
G
V
R
E
A
S
A
A
S
S
D
T
S
Site 397
S2482
V
R
E
A
S
A
A
S
S
D
T
S
S
A
K
Site 398
S2483
R
E
A
S
A
A
S
S
D
T
S
S
A
K
A
Site 399
S2486
S
A
A
S
S
D
T
S
S
A
K
A
A
G
G
Site 400
S2487
A
A
S
S
D
T
S
S
A
K
A
A
G
G
M
Site 401
T2519
G
E
G
R
T
H
M
T
K
S
D
S
L
P
S
Site 402
S2521
G
R
T
H
M
T
K
S
D
S
L
P
S
F
R
Site 403
S2523
T
H
M
T
K
S
D
S
L
P
S
F
R
V
S
Site 404
S2526
T
K
S
D
S
L
P
S
F
R
V
S
T
L
P
Site 405
S2530
S
L
P
S
F
R
V
S
T
L
P
L
E
S
H
Site 406
T2531
L
P
S
F
R
V
S
T
L
P
L
E
S
H
H
Site 407
S2536
V
S
T
L
P
L
E
S
H
H
P
D
P
N
T
Site 408
T2543
S
H
H
P
D
P
N
T
M
G
G
A
S
H
R
Site 409
S2548
P
N
T
M
G
G
A
S
H
R
D
R
A
L
S
Site 410
S2555
S
H
R
D
R
A
L
S
V
T
A
T
V
G
E
Site 411
T2557
R
D
R
A
L
S
V
T
A
T
V
G
E
T
K
Site 412
T2559
R
A
L
S
V
T
A
T
V
G
E
T
K
G
K
Site 413
T2586
Q
N
V
G
R
D
V
T
K
P
S
P
A
P
N
Site 414
S2589
G
R
D
V
T
K
P
S
P
A
P
N
T
D
R
Site 415
T2594
K
P
S
P
A
P
N
T
D
R
P
I
S
L
S
Site 416
S2599
P
N
T
D
R
P
I
S
L
S
N
E
K
D
F
Site 417
S2601
T
D
R
P
I
S
L
S
N
E
K
D
F
V
V
Site 418
S2616
R
Q
R
R
G
K
E
S
L
R
S
S
P
H
K
Site 419
S2619
R
G
K
E
S
L
R
S
S
P
H
K
K
A
L
Site 420
S2620
G
K
E
S
L
R
S
S
P
H
K
K
A
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation