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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
calsequestrin 2
Full Name:
Calsequestrin-2
Alias:
calsequestrin 2 (cardiac muscle); calsequestrin, cardiac muscle isoform; CAQ2; CASQ2; PDIB2
Type:
Calcium-binding protein
Mass (Da):
46436
Number AA:
399
UniProt ID:
O14958
International Prot ID:
IPI00298933
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0033018
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0007507
GO:0006941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y28
E
G
L
N
F
P
T
Y
D
G
K
D
R
V
V
Site 2
S36
D
G
K
D
R
V
V
S
L
S
E
K
N
F
K
Site 3
S38
K
D
R
V
V
S
L
S
E
K
N
F
K
Q
V
Site 4
Y55
K
Y
D
L
L
C
L
Y
Y
H
E
P
V
S
S
Site 5
Y56
Y
D
L
L
C
L
Y
Y
H
E
P
V
S
S
D
Site 6
S61
L
Y
Y
H
E
P
V
S
S
D
K
V
T
Q
K
Site 7
S62
Y
Y
H
E
P
V
S
S
D
K
V
T
Q
K
Q
Site 8
T66
P
V
S
S
D
K
V
T
Q
K
Q
F
Q
L
K
Site 9
S113
L
G
F
D
E
E
G
S
L
Y
I
L
K
G
D
Site 10
Y115
F
D
E
E
G
S
L
Y
I
L
K
G
D
R
T
Site 11
T122
Y
I
L
K
G
D
R
T
I
E
F
D
G
E
F
Site 12
S173
K
L
I
G
F
F
K
S
E
D
S
E
Y
Y
K
Site 13
S176
G
F
F
K
S
E
D
S
E
Y
Y
K
A
F
E
Site 14
Y178
F
K
S
E
D
S
E
Y
Y
K
A
F
E
E
A
Site 15
Y179
K
S
E
D
S
E
Y
Y
K
A
F
E
E
A
A
Site 16
S208
K
G
V
A
K
K
L
S
L
K
M
N
E
V
D
Site 17
Y217
K
M
N
E
V
D
F
Y
E
P
F
M
D
E
P
Site 18
T233
A
I
P
N
K
P
Y
T
E
E
E
L
V
E
F
Site 19
T248
V
K
E
H
Q
R
P
T
L
R
R
L
R
P
E
Site 20
T260
R
P
E
E
M
F
E
T
W
E
D
D
L
N
G
Site 21
S277
I
V
A
F
A
E
K
S
D
P
D
G
Y
E
F
Site 22
Y282
E
K
S
D
P
D
G
Y
E
F
L
E
I
L
K
Site 23
T296
K
Q
V
A
R
D
N
T
D
N
P
D
L
S
I
Site 24
S302
N
T
D
N
P
D
L
S
I
L
W
I
D
P
D
Site 25
T354
P
D
D
D
D
L
P
T
A
E
E
L
E
D
W
Site 26
S367
D
W
I
E
D
V
L
S
G
K
I
N
T
E
D
Site 27
T372
V
L
S
G
K
I
N
T
E
D
D
D
E
D
D
Site 28
S385
D
D
D
D
D
D
N
S
D
E
E
D
N
D
D
Site 29
S393
D
E
E
D
N
D
D
S
D
D
D
D
D
E
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation