PhosphoNET

           
Protein Info 
   
Short Name:  DVL1
Full Name:  Segment polarity protein dishevelled homolog DVL-1
Alias:  Dishevelled, dsh homolog 1 (Drosophila); Dishevelled, dsh homolog 1 (Drosophila), isoform CRAc; Dishevelled-1; DSH homolog 1; DSH homolog 1-like; DSH homologue 1; DVL; Putative uncharacterized protein DVL1; Segment polarity protein dishevelled homolog DVL-1-like; Segment polarity protein dishevelled homologue DVL-1
Type:  Inhibitor protein
Mass (Da):  75187
Number AA:  695
UniProt ID:  O14640
International Prot ID:  IPI00643229
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016023  GO:0045202  GO:0019717 Uniprot OncoNet
Molecular Function:  GO:0042802  GO:0004871   PhosphoSite+ KinaseNET
Biological Process:  GO:0060070  GO:0048813  GO:0007242 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T15YHMDEEETPYLVKLP
Site 2Y17MDEEETPYLVKLPVA
Site 3T29PVAPERVTLADFKNV
Site 4S38ADFKNVLSNRPVHAY
Site 5Y45SNRPVHAYKFFFKSM
Site 6S89VLAEGAHSDAGSQGT
Site 7S93GAHSDAGSQGTDSHT
Site 8T96SDAGSQGTDSHTDLP
Site 9S98AGSQGTDSHTDLPPP
Site 10T100SQGTDSHTDLPPPLE
Site 11S115RTGGIGDSRPPSFHP
Site 12S119IGDSRPPSFHPNVAS
Site 13S126SFHPNVASSRDGMDN
Site 14T135RDGMDNETGTESMVS
Site 15T137GMDNETGTESMVSHR
Site 16S139DNETGTESMVSHRRE
Site 17S142TGTESMVSHRRERAR
Site 18T159NREEAARTNGHPRGD
Site 19S177DVGLPPDSASTALSS
Site 20S179GLPPDSASTALSSEL
Site 21S183DSASTALSSELESSS
Site 22S184SASTALSSELESSSF
Site 23S188ALSSELESSSFVDSD
Site 24S189LSSELESSSFVDSDE
Site 25S190SSELESSSFVDSDED
Site 26S194ESSSFVDSDEDGSTS
Site 27S199VDSDEDGSTSRLSSS
Site 28T200DSDEDGSTSRLSSST
Site 29S201SDEDGSTSRLSSSTE
Site 30S204DGSTSRLSSSTEQST
Site 31S205GSTSRLSSSTEQSTS
Site 32S206STSRLSSSTEQSTSS
Site 33T207TSRLSSSTEQSTSSR
Site 34S210LSSSTEQSTSSRLIR
Site 35S212SSTEQSTSSRLIRKH
Site 36S213STEQSTSSRLIRKHK
Site 37S235LRQADRASSFSSITD
Site 38S236RQADRASSFSSITDS
Site 39S238ADRASSFSSITDSTM
Site 40S239DRASSFSSITDSTMS
Site 41T241ASSFSSITDSTMSLN
Site 42S265RHHFLGISIVGQSND
Site 43S270GISIVGQSNDRGDGG
Site 44Y279DRGDGGIYIGSIMKG
Site 45T334QTGPISLTVAKCWDP
Site 46T342VAKCWDPTPRSYFTV
Site 47Y346WDPTPRSYFTVPRAD
Site 48T348PTPRSYFTVPRADPV
Site 49Y377LTGALPRYGTSPCSS
Site 50T379GALPRYGTSPCSSAV
Site 51S380ALPRYGTSPCSSAVT
Site 52S383RYGTSPCSSAVTRTS
Site 53S384YGTSPCSSAVTRTSS
Site 54T387SPCSSAVTRTSSSSL
Site 55T389CSSAVTRTSSSSLTS
Site 56S390SSAVTRTSSSSLTSS
Site 57S391SAVTRTSSSSLTSSV
Site 58S392AVTRTSSSSLTSSVP
Site 59S393VTRTSSSSLTSSVPG
Site 60T395RTSSSSLTSSVPGAP
Site 61S396TSSSSLTSSVPGAPQ
Site 62S397SSSSLTSSVPGAPQL
Site 63T410QLEEAPLTVKSDMSA
Site 64S427RVMQLPDSGLEIRDR
Site 65Y455ADVVDWLYTHVEGFK
Site 66Y470ERREARKYASSLLKH
Site 67S473EARKYASSLLKHGFL
Site 68T483KHGFLRHTVNKITFS
Site 69T506DLCSNLATLNLNSGS
Site 70S511LATLNLNSGSSGTSD
Site 71S513TLNLNSGSSGTSDQD
Site 72S517NSGSSGTSDQDTLAP
Site 73T521SGTSDQDTLAPLPHP
Site 74Y538PWPLGQGYPYQYPGP
Site 75Y540PLGQGYPYQYPGPPP
Site 76Y542GQGYPYQYPGPPPCF
Site 77Y553PPCFPPAYQDPGFSY
Site 78S559AYQDPGFSYGSGSTG
Site 79Y560YQDPGFSYGSGSTGS
Site 80S562DPGFSYGSGSTGSQQ
Site 81S564GFSYGSGSTGSQQSE
Site 82S567YGSGSTGSQQSEGSK
Site 83S570GSTGSQQSEGSKSSG
Site 84S573GSQQSEGSKSSGSTR
Site 85S575QQSEGSKSSGSTRSS
Site 86S576QSEGSKSSGSTRSSR
Site 87S578EGSKSSGSTRSSRRA
Site 88T579GSKSSGSTRSSRRAP
Site 89S581KSSGSTRSSRRAPGR
Site 90S582SSGSTRSSRRAPGRE
Site 91S600RAAGAGGSGSESDHT
Site 92S602AGAGGSGSESDHTAP
Site 93S604AGGSGSESDHTAPSG
Site 94T607SGSESDHTAPSGVGS
Site 95S610ESDHTAPSGVGSSWR
Site 96S614TAPSGVGSSWRERPA
Site 97S615APSGVGSSWRERPAG
Site 98S625ERPAGQLSRGSSPRS
Site 99S628AGQLSRGSSPRSQAS
Site 100S629GQLSRGSSPRSQASA
Site 101S632SRGSSPRSQASATAP
Site 102S635SSPRSQASATAPGLP
Site 103T637PRSQASATAPGLPPP
Site 104Y651PHPTTKAYTVVGGPP
Site 105T652HPTTKAYTVVGGPPG
Site 106T674AAVPPELTGSRQSFQ
Site 107S676VPPELTGSRQSFQKA
Site 108S679ELTGSRQSFQKAMGN
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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