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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
N-WASP
Full Name:
Neural Wiskott-Aldrich syndrome protein
Alias:
NWASP; WASL; Wiskott-Aldrich syndrome-like
Type:
Adapter/scaffold protein
Mass (Da):
54827
Number AA:
505
UniProt ID:
O00401
International Prot ID:
IPI00011676
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005083
PhosphoSite+
KinaseNET
Biological Process:
GO:0008154
GO:0006928
GO:0006461
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
P
P
P
P
R
R
V
T
N
V
G
S
L
L
L
Site 2
S19
R
R
V
T
N
V
G
S
L
L
L
T
P
Q
E
Site 3
T23
N
V
G
S
L
L
L
T
P
Q
E
N
E
S
L
Site 4
S29
L
T
P
Q
E
N
E
S
L
F
T
F
L
G
K
Site 5
T32
Q
E
N
E
S
L
F
T
F
L
G
K
K
C
V
Site 6
S58
A
D
R
N
C
M
W
S
K
K
C
S
G
V
A
Site 7
Y76
K
D
N
P
Q
R
S
Y
F
L
R
I
F
D
I
Site 8
Y95
L
L
W
E
Q
E
L
Y
N
N
F
V
Y
N
S
Site 9
Y100
E
L
Y
N
N
F
V
Y
N
S
P
R
G
Y
F
Site 10
Y106
V
Y
N
S
P
R
G
Y
F
H
T
F
A
G
D
Site 11
T109
S
P
R
G
Y
F
H
T
F
A
G
D
T
C
Q
Site 12
T135
K
K
F
R
K
A
V
T
D
L
L
G
R
R
Q
Site 13
S145
L
G
R
R
Q
R
K
S
E
K
R
R
D
P
P
Site 14
Y175
E
I
T
T
N
R
F
Y
G
P
Q
V
N
N
I
Site 15
T199
K
A
K
K
K
R
L
T
K
A
D
I
G
T
P
Site 16
T205
L
T
K
A
D
I
G
T
P
S
N
F
Q
H
I
Site 17
S242
L
F
D
M
C
G
I
S
E
A
Q
L
K
D
R
Site 18
T251
A
Q
L
K
D
R
E
T
S
K
V
I
Y
D
F
Site 19
S252
Q
L
K
D
R
E
T
S
K
V
I
Y
D
F
I
Site 20
Y256
R
E
T
S
K
V
I
Y
D
F
I
E
K
T
G
Site 21
T262
I
Y
D
F
I
E
K
T
G
G
V
E
A
V
K
Site 22
S283
A
P
P
P
P
P
P
S
R
G
G
P
P
P
P
Site 23
S297
P
P
P
P
P
H
N
S
G
P
P
P
P
P
A
Site 24
S315
G
A
P
P
P
P
P
S
R
A
P
T
A
A
P
Site 25
T319
P
P
P
S
R
A
P
T
A
A
P
P
P
P
P
Site 26
S328
A
P
P
P
P
P
P
S
R
P
S
V
A
V
P
Site 27
S331
P
P
P
P
S
R
P
S
V
A
V
P
P
P
P
Site 28
Y343
P
P
P
P
N
R
M
Y
P
P
P
P
P
A
L
Site 29
S352
P
P
P
P
A
L
P
S
S
A
P
S
G
P
P
Site 30
S353
P
P
P
A
L
P
S
S
A
P
S
G
P
P
P
Site 31
S356
A
L
P
S
S
A
P
S
G
P
P
P
P
P
P
Site 32
S393
P
P
P
P
G
L
P
S
D
G
D
H
Q
V
P
Site 33
S426
L
K
K
V
E
Q
N
S
R
P
V
S
C
S
G
Site 34
S430
E
Q
N
S
R
P
V
S
C
S
G
R
D
A
L
Site 35
S432
N
S
R
P
V
S
C
S
G
R
D
A
L
L
D
Site 36
S449
R
Q
G
I
Q
L
K
S
V
A
D
G
Q
E
S
Site 37
S456
S
V
A
D
G
Q
E
S
T
P
P
T
P
A
P
Site 38
T457
V
A
D
G
Q
E
S
T
P
P
T
P
A
P
T
Site 39
T460
G
Q
E
S
T
P
P
T
P
A
P
T
S
G
I
Site 40
T464
T
P
P
T
P
A
P
T
S
G
I
V
G
A
L
Site 41
S484
K
R
S
K
A
I
H
S
S
D
E
D
E
D
E
Site 42
S485
R
S
K
A
I
H
S
S
D
E
D
E
D
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation