PhosphoNET

           
Protein Info 
   
Short Name:  eIF3-epsilon
Full Name:  Eukaryotic translation initiation factor 3 subunit F
Alias:  EIF-3 epsilon; EIF3 p47 subunit; EIF3f; EIF3-p47; EIF3S5; Eukaryotic translation initiation factor 3, subunit F; IF35
Type:  Protein synthesis protein, Translation
Mass (Da):  37564
Number AA:  357
UniProt ID:  O00303
International Prot ID:  IPI00654777
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005852   Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0003743   PhosphoSite+ KinaseNET
Biological Process:  GO:0006413     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S46PAAAPASSSDPAAAA
Site 2T62ATAAPGQTPASAQAP
Site 3S65APGQTPASAQAPAQT
Site 4T72SAQAPAQTPAPALPG
Site 5S105ILASIVDSYERRNEG
Site 6Y106LASIVDSYERRNEGA
Site 7T119GAARVIGTLLGTVDK
Site 8T132DKHSVEVTNCFSVPH
Site 9S164YELHKKVSPNELILG
Site 10T180YATGHDITEHSVLIH
Site 11Y189HSVLIHEYYSREAPN
Site 12Y190SVLIHEYYSREAPNP
Site 13T201APNPIHLTVDTSLQN
Site 14S205IHLTVDTSLQNGRMS
Site 15S212SLQNGRMSIKAYVST
Site 16Y216GRMSIKAYVSTLMGV
Site 17Y241PLTVKYAYYDTERIG
Site 18Y242LTVKYAYYDTERIGV
Site 19T244VKYAYYDTERIGVDL
Site 20T255GVDLIMKTCFSPNRV
Site 21S258LIMKTCFSPNRVIGL
Site 22S266PNRVIGLSSDLQQVG
Site 23S267NRVIGLSSDLQQVGG
Site 24S284ARIQDALSTVLQYAE
Site 25S295QYAEDVLSGKVSADN
Site 26S299DVLSGKVSADNTVGR
Site 27T303GKVSADNTVGRFLMS
Site 28T325IVPDDFETMLNSNIN
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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