KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CLIC1
Full Name:
Chloride intracellular channel protein 1
Alias:
Chloride channel ABP; G6; NCC27; Nuclear chloride ion channel 27; p64 CLCP; p64CLCP; Regulatory nuclear chloride ion channel protein; RNCC protein
Type:
Channel, chloride
Mass (Da):
26923
Number AA:
241
UniProt ID:
O00299
International Prot ID:
IPI00010896
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005903
GO:0034707
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0031404
GO:0005515
GO:0005247
PhosphoSite+
KinaseNET
Biological Process:
GO:0006821
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
E
L
F
V
K
A
G
S
D
G
A
K
I
G
N
Site 2
T48
F
N
V
T
T
V
D
T
K
R
R
T
E
T
V
Site 3
T52
T
V
D
T
K
R
R
T
E
T
V
Q
K
L
C
Site 4
T54
D
T
K
R
R
T
E
T
V
Q
K
L
C
P
G
Site 5
Y69
G
Q
L
P
F
L
L
Y
G
T
E
V
H
T
D
Site 6
T77
G
T
E
V
H
T
D
T
N
K
I
E
E
F
L
Site 7
Y93
A
V
L
C
P
P
R
Y
P
K
L
A
A
L
N
Site 8
S103
L
A
A
L
N
P
E
S
N
T
A
G
L
D
I
Site 9
S121
F
S
A
Y
I
K
N
S
N
P
A
L
N
D
N
Site 10
Y143
A
L
K
V
L
D
N
Y
L
T
S
P
L
P
E
Site 11
S146
V
L
D
N
Y
L
T
S
P
L
P
E
E
V
D
Site 12
T155
L
P
E
E
V
D
E
T
S
A
E
D
E
G
V
Site 13
S156
P
E
E
V
D
E
T
S
A
E
D
E
G
V
S
Site 14
S163
S
A
E
D
E
G
V
S
Q
R
K
F
L
D
G
Site 15
T198
C
K
K
Y
R
G
F
T
I
P
E
A
F
R
G
Site 16
Y209
A
F
R
G
V
H
R
Y
L
S
N
A
Y
A
R
Site 17
S211
R
G
V
H
R
Y
L
S
N
A
Y
A
R
E
E
Site 18
S221
Y
A
R
E
E
F
A
S
T
C
P
D
D
E
E
Site 19
T222
A
R
E
E
F
A
S
T
C
P
D
D
E
E
I
Site 20
Y233
D
E
E
I
E
L
A
Y
E
Q
V
A
K
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation