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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CLIM1
Full Name:
PDZ and LIM domain protein 1
Alias:
Carboxyl terminal LIM domain protein 1; CLP36; CLP-36; C-terminal LIM domain protein 1; Elfin; LIM domain protein CLP-36; PDL1; PDLI1; PDLIM1; PDZ and LIM domain 1
Type:
Cytoskeletal protein
Mass (Da):
36072
Number AA:
329
UniProt ID:
O00151
International Prot ID:
IPI00010414
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006979
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
F
E
Q
P
L
A
I
S
R
V
T
P
G
S
K
Site 2
T34
P
L
A
I
S
R
V
T
P
G
S
K
A
A
L
Site 3
S59
A
I
D
G
E
N
T
S
N
M
T
H
L
E
A
Site 4
T74
Q
N
R
I
K
G
C
T
D
N
L
T
L
T
V
Site 5
T78
K
G
C
T
D
N
L
T
L
T
V
A
R
S
E
Site 6
T80
C
T
D
N
L
T
L
T
V
A
R
S
E
H
K
Site 7
S84
L
T
L
T
V
A
R
S
E
H
K
V
W
S
P
Site 8
S90
R
S
E
H
K
V
W
S
P
L
V
T
E
E
G
Site 9
T94
K
V
W
S
P
L
V
T
E
E
G
K
R
H
P
Site 10
Y102
E
E
G
K
R
H
P
Y
K
M
N
L
A
S
E
Site 11
S108
P
Y
K
M
N
L
A
S
E
P
Q
E
V
L
H
Site 12
S118
Q
E
V
L
H
I
G
S
A
H
N
R
S
A
M
Site 13
S123
I
G
S
A
H
N
R
S
A
M
P
F
T
A
S
Site 14
T128
N
R
S
A
M
P
F
T
A
S
P
A
S
S
T
Site 15
S130
S
A
M
P
F
T
A
S
P
A
S
S
T
T
A
Site 16
S133
F
T
A
S
P
A
S
S
T
T
A
R
V
I
T
Site 17
T136
A
S
P
A
S
S
T
T
A
R
V
I
T
N
Q
Site 18
T141
S
T
T
A
R
V
I
T
N
Q
Y
N
N
P
A
Site 19
Y144
A
R
V
I
T
N
Q
Y
N
N
P
A
G
L
Y
Site 20
Y151
Y
N
N
P
A
G
L
Y
S
S
E
N
I
S
N
Site 21
S153
N
P
A
G
L
Y
S
S
E
N
I
S
N
F
N
Site 22
S157
L
Y
S
S
E
N
I
S
N
F
N
N
A
L
E
Site 23
S165
N
F
N
N
A
L
E
S
K
T
A
A
S
G
V
Site 24
S186
L
D
H
A
Q
P
P
S
S
L
V
I
D
K
E
Site 25
S187
D
H
A
Q
P
P
S
S
L
V
I
D
K
E
S
Site 26
S194
S
L
V
I
D
K
E
S
E
V
Y
K
M
L
Q
Site 27
Y197
I
D
K
E
S
E
V
Y
K
M
L
Q
E
K
Q
Site 28
S213
L
N
E
P
P
K
Q
S
T
S
F
L
V
L
Q
Site 29
T214
N
E
P
P
K
Q
S
T
S
F
L
V
L
Q
E
Site 30
S215
E
P
P
K
Q
S
T
S
F
L
V
L
Q
E
I
Site 31
S225
V
L
Q
E
I
L
E
S
E
E
K
G
D
P
N
Site 32
S235
K
G
D
P
N
K
P
S
G
F
R
S
V
K
A
Site 33
S239
N
K
P
S
G
F
R
S
V
K
A
P
V
T
K
Site 34
Y306
F
F
V
E
D
Q
I
Y
C
E
K
H
A
R
E
Site 35
T316
K
H
A
R
E
R
V
T
P
P
E
G
Y
E
V
Site 36
Y321
R
V
T
P
P
E
G
Y
E
V
V
T
V
F
P
Site 37
T325
P
E
G
Y
E
V
V
T
V
F
P
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation