KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SMTNL1
Full Name:
Smoothelin-like protein 1
Alias:
Calponiny-associated smooth muscle protein; CHASM; Smoothelin-like 1; SMTL1
Type:
Mass (Da):
48934
Number AA:
457
UniProt ID:
A8MU46
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
Q
K
E
G
K
L
S
E
D
G
T
T
V
S
Site 2
T13
G
K
L
S
E
D
G
T
T
V
S
P
A
A
D
Site 3
T14
K
L
S
E
D
G
T
T
V
S
P
A
A
D
N
Site 4
S16
S
E
D
G
T
T
V
S
P
A
A
D
N
P
E
Site 5
T48
A
I
N
E
G
P
P
T
E
S
G
K
Q
E
K
Site 6
S50
N
E
G
P
P
T
E
S
G
K
Q
E
K
A
P
Site 7
S63
A
P
A
E
D
G
M
S
A
E
L
Q
G
E
A
Site 8
S80
L
D
E
V
K
V
E
S
Q
R
E
A
G
G
K
Site 9
T104
E
D
G
E
K
E
E
T
T
V
G
S
Q
E
M
Site 10
T105
D
G
E
K
E
E
T
T
V
G
S
Q
E
M
T
Site 11
S108
K
E
E
T
T
V
G
S
Q
E
M
T
G
R
K
Site 12
T112
T
V
G
S
Q
E
M
T
G
R
K
E
E
T
K
Site 13
S120
G
R
K
E
E
T
K
S
E
P
K
E
A
E
E
Site 14
S130
K
E
A
E
E
K
E
S
T
L
A
S
E
K
Q
Site 15
T131
E
A
E
E
K
E
S
T
L
A
S
E
K
Q
K
Site 16
S134
E
K
E
S
T
L
A
S
E
K
Q
K
A
E
E
Site 17
S148
E
K
E
A
K
P
E
S
G
Q
K
A
D
A
N
Site 18
T165
D
K
P
E
P
K
A
T
V
E
E
E
D
A
K
Site 19
T173
V
E
E
E
D
A
K
T
A
S
Q
E
E
T
V
Site 20
T179
K
T
A
S
Q
E
E
T
V
V
E
D
E
A
K
Site 21
S211
E
E
A
D
E
P
G
S
P
S
E
E
Q
E
Q
Site 22
S233
G
G
A
G
V
I
P
S
S
P
E
E
W
P
E
Site 23
S234
G
A
G
V
I
P
S
S
P
E
E
W
P
E
S
Site 24
S241
S
P
E
E
W
P
E
S
P
T
G
E
G
H
N
Site 25
S250
T
G
E
G
H
N
L
S
T
D
G
L
G
P
D
Site 26
T251
G
E
G
H
N
L
S
T
D
G
L
G
P
D
C
Site 27
S261
L
G
P
D
C
V
A
S
G
Q
T
S
P
S
A
Site 28
S265
C
V
A
S
G
Q
T
S
P
S
A
S
E
S
S
Site 29
S267
A
S
G
Q
T
S
P
S
A
S
E
S
S
P
S
Site 30
S269
G
Q
T
S
P
S
A
S
E
S
S
P
S
D
V
Site 31
S271
T
S
P
S
A
S
E
S
S
P
S
D
V
P
Q
Site 32
S272
S
P
S
A
S
E
S
S
P
S
D
V
P
Q
S
Site 33
S274
S
A
S
E
S
S
P
S
D
V
P
Q
S
P
P
Site 34
S279
S
P
S
D
V
P
Q
S
P
P
E
S
P
S
S
Site 35
S283
V
P
Q
S
P
P
E
S
P
S
S
G
E
K
K
Site 36
S286
S
P
P
E
S
P
S
S
G
E
K
K
E
K
A
Site 37
S299
K
A
P
E
R
R
V
S
A
P
A
R
P
R
G
Site 38
S324
D
K
F
G
G
A
A
S
G
P
T
A
L
F
R
Site 39
T333
P
T
A
L
F
R
N
T
K
A
A
G
A
A
I
Site 40
Y358
C
R
A
M
T
K
K
Y
E
H
V
D
I
Q
N
Site 41
S367
H
V
D
I
Q
N
F
S
S
S
W
S
S
G
M
Site 42
S368
V
D
I
Q
N
F
S
S
S
W
S
S
G
M
A
Site 43
S369
D
I
Q
N
F
S
S
S
W
S
S
G
M
A
F
Site 44
S371
Q
N
F
S
S
S
W
S
S
G
M
A
F
C
A
Site 45
Y390
F
F
P
D
A
F
D
Y
A
E
L
D
P
A
K
Site 46
T403
A
K
R
R
H
N
F
T
L
A
F
S
T
A
E
Site 47
S407
H
N
F
T
L
A
F
S
T
A
E
K
L
A
D
Site 48
Y436
V
P
D
S
K
C
V
Y
T
Y
I
Q
E
L
Y
Site 49
T437
P
D
S
K
C
V
Y
T
Y
I
Q
E
L
Y
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation