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Updated November 2019
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Protein Info
Short Name:
POM121B
Full Name:
Putative nuclear envelope pore membrane protein POM 121B
Alias:
Type:
Nucleus, Nuclear pore complex protein
Mass (Da):
83015
Number AA:
834
UniProt ID:
A6NF01
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005643
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0051028
GO:0015031
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
S
R
R
V
R
T
S
E
L
W
K
R
N
Site 2
S8
M
S
R
R
V
R
T
S
E
L
W
K
R
N
G
Site 3
S17
L
W
K
R
N
G
P
S
S
S
P
F
S
S
P
Site 4
S18
W
K
R
N
G
P
S
S
S
P
F
S
S
P
A
Site 5
S19
K
R
N
G
P
S
S
S
P
F
S
S
P
A
S
Site 6
S22
G
P
S
S
S
P
F
S
S
P
A
S
S
R
S
Site 7
S23
P
S
S
S
P
F
S
S
P
A
S
S
R
S
Q
Site 8
S26
S
P
F
S
S
P
A
S
S
R
S
Q
T
P
E
Site 9
S27
P
F
S
S
P
A
S
S
R
S
Q
T
P
E
R
Site 10
S29
S
S
P
A
S
S
R
S
Q
T
P
E
R
P
A
Site 11
T31
P
A
S
S
R
S
Q
T
P
E
R
P
A
K
K
Site 12
S48
E
E
E
M
C
H
H
S
S
S
S
T
P
L
A
Site 13
S50
E
M
C
H
H
S
S
S
S
T
P
L
A
A
D
Site 14
T52
C
H
H
S
S
S
S
T
P
L
A
A
D
K
E
Site 15
S60
P
L
A
A
D
K
E
S
Q
G
E
K
A
A
D
Site 16
T69
G
E
K
A
A
D
T
T
P
R
K
K
Q
N
S
Site 17
S76
T
P
R
K
K
Q
N
S
N
S
Q
S
T
P
G
Site 18
S78
R
K
K
Q
N
S
N
S
Q
S
T
P
G
S
S
Site 19
S80
K
Q
N
S
N
S
Q
S
T
P
G
S
S
G
Q
Site 20
T81
Q
N
S
N
S
Q
S
T
P
G
S
S
G
Q
R
Site 21
S84
N
S
Q
S
T
P
G
S
S
G
Q
R
K
R
K
Site 22
S85
S
Q
S
T
P
G
S
S
G
Q
R
K
R
K
V
Site 23
S97
R
K
V
Q
L
L
P
S
R
R
G
E
Q
L
T
Site 24
T104
S
R
R
G
E
Q
L
T
L
P
P
P
P
Q
L
Site 25
S127
L
D
L
E
K
K
A
S
L
Q
W
F
N
Q
A
Site 26
S139
N
Q
A
L
E
D
K
S
D
A
A
S
N
S
V
Site 27
S143
E
D
K
S
D
A
A
S
N
S
V
T
E
T
P
Site 28
S145
K
S
D
A
A
S
N
S
V
T
E
T
P
P
I
Site 29
T147
D
A
A
S
N
S
V
T
E
T
P
P
I
T
Q
Site 30
T149
A
S
N
S
V
T
E
T
P
P
I
T
Q
P
S
Site 31
T153
V
T
E
T
P
P
I
T
Q
P
S
F
T
F
T
Site 32
S172
A
P
A
S
P
P
T
S
L
L
A
P
S
T
N
Site 33
S177
P
T
S
L
L
A
P
S
T
N
P
L
L
E
S
Site 34
S184
S
T
N
P
L
L
E
S
L
K
K
M
Q
T
P
Site 35
T190
E
S
L
K
K
M
Q
T
P
P
S
L
P
P
C
Site 36
S193
K
K
M
Q
T
P
P
S
L
P
P
C
P
E
S
Site 37
S200
S
L
P
P
C
P
E
S
A
G
A
A
T
T
E
Site 38
T206
E
S
A
G
A
A
T
T
E
A
L
S
P
P
K
Site 39
S210
A
A
T
T
E
A
L
S
P
P
K
T
P
N
L
Site 40
T214
E
A
L
S
P
P
K
T
P
N
L
L
P
P
L
Site 41
S226
P
P
L
G
L
S
Q
S
G
P
P
G
L
L
P
Site 42
S234
G
P
P
G
L
L
P
S
P
S
F
D
S
N
P
Site 43
S236
P
G
L
L
P
S
P
S
F
D
S
N
P
P
T
Site 44
S239
L
P
S
P
S
F
D
S
N
P
P
T
T
L
L
Site 45
T258
A
P
S
M
V
P
A
T
D
T
K
A
P
P
T
Site 46
T260
S
M
V
P
A
T
D
T
K
A
P
P
T
L
Q
Site 47
T277
T
T
T
K
P
Q
A
T
S
A
P
S
P
A
P
Site 48
S281
P
Q
A
T
S
A
P
S
P
A
P
K
Q
S
F
Site 49
S287
P
S
P
A
P
K
Q
S
F
L
F
G
T
Q
N
Site 50
T292
K
Q
S
F
L
F
G
T
Q
N
T
S
P
S
S
Site 51
T295
F
L
F
G
T
Q
N
T
S
P
S
S
P
A
A
Site 52
S296
L
F
G
T
Q
N
T
S
P
S
S
P
A
A
P
Site 53
S298
G
T
Q
N
T
S
P
S
S
P
A
A
P
A
A
Site 54
S299
T
Q
N
T
S
P
S
S
P
A
A
P
A
A
S
Site 55
S306
S
P
A
A
P
A
A
S
S
A
S
P
M
F
K
Site 56
S307
P
A
A
P
A
A
S
S
A
S
P
M
F
K
P
Site 57
T317
P
M
F
K
P
I
F
T
A
P
P
K
S
E
K
Site 58
S322
I
F
T
A
P
P
K
S
E
K
E
G
P
T
P
Site 59
T328
K
S
E
K
E
G
P
T
P
P
G
P
S
V
S
Site 60
S333
G
P
T
P
P
G
P
S
V
S
A
T
A
P
S
Site 61
S335
T
P
P
G
P
S
V
S
A
T
A
P
S
S
S
Site 62
T337
P
G
P
S
V
S
A
T
A
P
S
S
S
S
L
Site 63
S340
S
V
S
A
T
A
P
S
S
S
S
L
P
T
T
Site 64
S341
V
S
A
T
A
P
S
S
S
S
L
P
T
T
T
Site 65
S342
S
A
T
A
P
S
S
S
S
L
P
T
T
T
S
Site 66
S343
A
T
A
P
S
S
S
S
L
P
T
T
T
S
T
Site 67
T346
P
S
S
S
S
L
P
T
T
T
S
T
T
A
P
Site 68
T347
S
S
S
S
L
P
T
T
T
S
T
T
A
P
T
Site 69
S349
S
S
L
P
T
T
T
S
T
T
A
P
T
F
Q
Site 70
T350
S
L
P
T
T
T
S
T
T
A
P
T
F
Q
P
Site 71
T354
T
T
S
T
T
A
P
T
F
Q
P
V
F
S
S
Site 72
S360
P
T
F
Q
P
V
F
S
S
M
G
P
P
A
S
Site 73
T378
P
A
P
F
F
K
Q
T
T
T
P
A
T
A
P
Site 74
T380
P
F
F
K
Q
T
T
T
P
A
T
A
P
T
T
Site 75
T406
T
S
A
V
A
P
I
T
S
A
S
P
S
T
D
Site 76
S407
S
A
V
A
P
I
T
S
A
S
P
S
T
D
S
Site 77
S409
V
A
P
I
T
S
A
S
P
S
T
D
S
A
S
Site 78
S411
P
I
T
S
A
S
P
S
T
D
S
A
S
K
P
Site 79
T412
I
T
S
A
S
P
S
T
D
S
A
S
K
P
A
Site 80
S414
S
A
S
P
S
T
D
S
A
S
K
P
A
F
G
Site 81
S416
S
P
S
T
D
S
A
S
K
P
A
F
G
F
G
Site 82
S426
A
F
G
F
G
I
N
S
V
S
S
S
S
V
S
Site 83
S428
G
F
G
I
N
S
V
S
S
S
S
V
S
T
T
Site 84
S429
F
G
I
N
S
V
S
S
S
S
V
S
T
T
T
Site 85
S430
G
I
N
S
V
S
S
S
S
V
S
T
T
T
S
Site 86
S431
I
N
S
V
S
S
S
S
V
S
T
T
T
S
T
Site 87
S433
S
V
S
S
S
S
V
S
T
T
T
S
T
A
T
Site 88
T434
V
S
S
S
S
V
S
T
T
T
S
T
A
T
A
Site 89
T435
S
S
S
S
V
S
T
T
T
S
T
A
T
A
A
Site 90
S437
S
S
V
S
T
T
T
S
T
A
T
A
A
S
Q
Site 91
T477
K
P
P
A
L
P
T
T
T
T
V
T
T
F
S
Site 92
T479
P
A
L
P
T
T
T
T
V
T
T
F
S
Q
S
Site 93
T482
P
T
T
T
T
V
T
T
F
S
Q
S
L
P
T
Site 94
S512
F
G
S
T
L
A
T
S
A
P
A
T
S
S
Q
Site 95
T516
L
A
T
S
A
P
A
T
S
S
Q
P
T
L
T
Site 96
S518
T
S
A
P
A
T
S
S
Q
P
T
L
T
F
S
Site 97
T521
P
A
T
S
S
Q
P
T
L
T
F
S
N
T
S
Site 98
T523
T
S
S
Q
P
T
L
T
F
S
N
T
S
T
P
Site 99
S525
S
Q
P
T
L
T
F
S
N
T
S
T
P
T
F
Site 100
T527
P
T
L
T
F
S
N
T
S
T
P
T
F
N
I
Site 101
T529
L
T
F
S
N
T
S
T
P
T
F
N
I
P
F
Site 102
T531
F
S
N
T
S
T
P
T
F
N
I
P
F
G
S
Site 103
S538
T
F
N
I
P
F
G
S
S
A
K
S
P
L
P
Site 104
S539
F
N
I
P
F
G
S
S
A
K
S
P
L
P
S
Site 105
S542
P
F
G
S
S
A
K
S
P
L
P
S
Y
P
G
Site 106
S546
S
A
K
S
P
L
P
S
Y
P
G
A
N
P
Q
Site 107
Y547
A
K
S
P
L
P
S
Y
P
G
A
N
P
Q
P
Site 108
S578
L
T
P
S
F
G
S
S
F
T
F
G
N
S
A
Site 109
T580
P
S
F
G
S
S
F
T
F
G
N
S
A
A
P
Site 110
T613
V
P
T
P
I
Q
P
T
F
G
G
A
T
H
S
Site 111
S636
S
A
F
G
A
P
A
S
S
Q
P
A
F
G
G
Site 112
S637
A
F
G
A
P
A
S
S
Q
P
A
F
G
G
S
Site 113
S656
S
F
G
A
A
T
S
S
G
F
G
A
T
T
Q
Site 114
T662
S
S
G
F
G
A
T
T
Q
T
A
S
S
G
S
Site 115
T664
G
F
G
A
T
T
Q
T
A
S
S
G
S
S
S
Site 116
S666
G
A
T
T
Q
T
A
S
S
G
S
S
S
S
V
Site 117
S667
A
T
T
Q
T
A
S
S
G
S
S
S
S
V
F
Site 118
S670
Q
T
A
S
S
G
S
S
S
S
V
F
G
S
T
Site 119
S671
T
A
S
S
G
S
S
S
S
V
F
G
S
T
T
Site 120
S672
A
S
S
G
S
S
S
S
V
F
G
S
T
T
P
Site 121
S676
S
S
S
S
V
F
G
S
T
T
P
S
P
F
T
Site 122
T678
S
S
V
F
G
S
T
T
P
S
P
F
T
F
G
Site 123
T683
S
T
T
P
S
P
F
T
F
G
G
S
A
A
P
Site 124
S713
S
A
T
T
G
A
F
S
F
G
A
G
Q
S
G
Site 125
S719
F
S
F
G
A
G
Q
S
G
S
T
A
T
S
T
Site 126
S721
F
G
A
G
Q
S
G
S
T
A
T
S
T
P
F
Site 127
S725
Q
S
G
S
T
A
T
S
T
P
F
A
G
G
L
Site 128
T726
S
G
S
T
A
T
S
T
P
F
A
G
G
L
G
Site 129
T739
L
G
Q
N
A
L
G
T
T
G
Q
S
T
P
F
Site 130
S752
P
F
A
F
N
V
G
S
T
T
E
S
K
P
V
Site 131
S756
N
V
G
S
T
T
E
S
K
P
V
F
G
G
T
Site 132
T772
T
P
T
F
G
L
N
T
P
A
P
G
V
G
T
Site 133
T779
T
P
A
P
G
V
G
T
S
G
S
S
L
S
F
Site 134
S785
G
T
S
G
S
S
L
S
F
G
A
S
S
A
P
Site 135
S810
G
S
A
A
P
S
F
S
I
G
A
G
S
K
T
Site 136
T817
S
I
G
A
G
S
K
T
L
G
A
R
Q
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation